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We have represented thousands of people, including some of the largest and most important injury cases ever brought in the United States.

In the single largest damages case in the history of the world, our attorneys were selected by the Arizona Attorney General as the only Arizona law firm to represent the State against American tobacco companies. As a result, Arizona taxpayers will receive more than three billion dollars to cover the costs of treating tobacco-related illnesses, maintain educational programs to prevent young people from smoking, and fund other important State programs.

Your Legal Rights

If you or a loved one has experienced heart problems while using Avandia, you may be entitled to compensation.

You should act immediately to contact a lawyer experienced in matters involving dangerous pharmaceuticals.

study finds heart risk in avandia, diabetes drug
avandia side effects

May 22, 2007—A study published in The New England Journal of Medicine showed that Avandia significantly increased the risk of heart attacks, as compared to other diabetes drugs or a placebo.

Dr. Steven Nissen reviewed more than 40 clinical studies involving 28,000 patients. He estimates that tens of thousands of people had heart attacks as a result of Avandia.

GlaxoSmithKline has been aware of these concerns since at least August 2006 when it conducted a similar analysis. Notwithstanding its own analysis, GlaxoSmithKline defended the safety of Avandia and claimed the drug has a comparable cardiovascular profile to other oral antidiabetic medicines.

glaxosmithkline analysis finds 31 percent increase in heart risk

avandia heart attack

In August 2006, a similar analysis by GlaxoSmithKline identified a 31 percent increase in cardiovascular risk. Although the company alerted the FDA to the safety concerns, it did not notify doctors or patients of the heart problems associated with the drug.

The FDA has come under fire in recent years for its failures in protecting the public from dangerous drugs. Lawmakers quickly reacted to the news, questioning whether Avandia further evidenced a breakdown at the FDA.

Representative John D. Dinglee, chairman of the House Energy and Commerce Committee, noted that the FDA has known about the problem for at least eight months. "What we don't know is why diabetics and their doctors haven't been notified of the substantial risk to the heart from a drug prescribed to protect the cardiovascular system.

An editorial that accompanied the May 2007 study in The New England Journal Medicine questioned why doctors would continue to prescribe Avandia given the availability of alternative treatments with more favorable risk profiles.

Avandia has been on the market since 1999 and is approved for the treatment of Type 2 diabetes. It is sold alone as Avandia and in combination with other drugs, including Avandamet and Avandryl.

What You Should Do
avandia lawyers Our Lawyers Can Help

O'Steen & Harrison, PLC presently is investigating legal claims on behalf of those harmed by Avandia. We invite you to contact us for a free, confidential consultation about your legal rights.

We will represent patients throughout the United States. We can help you, too, wherever you live.

For free answers to your questions about Avandia, please call us toll-free at 1-800-883-8888 or complete this online contact form.